Improved specificity of the PABA test with p-aminosalicylic acid (PAS).

Improved specificity of the PABA test with p-aminosalicylic acid (PAS).

Until now use of the PABA test together with [14C] PABA to calculate the PABA excretion index has probably been the best adaptation suggested to enhance the specificity of this non-invasive pancreatic function test. Drawbacks of the method are the application of radioactivity, the fact that children, pregnant women, and patients with renal insufficiency have to be excluded from the test, and th...

Improved specificity of the PABA test with p -

Until now use of the PABA test together with ["C] PABA to calculate the PABA excretion index has probably been the best adaptation suggested to enhance the specificity of this non-invasive pancreatic function test. Drawbacks of the method are the application of radioactivity, the fact that children, pregnant women, and patients with renal insufficiency have to be excluded from the test, and the...

Para-Aminosalicylic Acid: Pas

Serum concentrations of para-aminosalicylic acid (PAS) produced by various forms of PAS.

Para-aminosalicylic acid (PAS) is now generally accepted as an effective antibacterial agent in the treatment of certain forms of tuberculosis when administered alone or in combination with one of the streptomycins. However, there remains a great deal of uncertainty as to the best method of administering the drug. Both the free acid and the sodium salt of PAS have been given in various dosage f...

Exocrine pancreatic function as determined in a same-day test with use of bentiromide and p-aminosalicylic acid.

We describe a new approach to the bentiromide test of exocrine pancreatic function, p-Aminosalicylic acid (PAS), a compound closely related to the bentiromide fragment p-aminobenzoic acid (PABA), is used as a marker of the pharmacokinetic behavior of PABA to derive a PABA excretion index. This index is identical to that derived with [14C]-PABA. Concentrations of both PABA and PAS are measured i...